Research Articles and Reviews:
71. Li, Q.-Y.; Zhang, H.-Y.; Liu, W.-B.* "Research Progress in Transition-Metal-Free C—Si Bond Formation". Chinese J. Org. Chem. 2023, 43, 3470.
70. Long, J.; Lu, Z.-W.; Li, X.-L.; Xue, P.; Liu, W.-B.* "Ni-Catalyzed Enantioselective Difunctionalization of Alkynes to Azepine Derivatives Bearing a Quaternary Center and anUnprotected Imine". Chin. J. Chem. 2023, 41
69. Peng, J.-H.; Zheng, Y.-Q.; Bai, L.-G.; Liu, W.-B.* "Chiral discrimination of small substituents in biaryl atropisomer construction: enantioselective synthesis of axially chiral
68. Zeng, H.-X.; Zhang, X.-W.; Li, Q.-Y.; Liu, W.-B.* "Enantioselective Ni-catalyzed syn-hydrometalative cyclization of alkyne-tethered ketoamides to α-hydroxy-γ-lactams". Org. Chem. Front. 2023, 10, 3883
67. Huang, H.-G.; Zheng, Y.-Q.; Zhong, D.; Deng, J.-L.; Liu, W.-B.* "Reductive Aza-Pauson-Khand Reaction of Nitriles". J. Am. Chem. Soc.2023, 145, 10463
66. Liu, W.-M.; Lu, Z.; Wei, Q.; Liu, W.-B.* "Enantioselective Nickel-Catalyzed Reductive anti-Arylative Annulation of Alkyne-Tethered Malononitriles to Construct Quaternary Stereocenters". Org. Lett. 2023, 25, 1811
65. Wang, X.; Yu, Z.-X.*; Liu, W.-B.*"Formal Hydrotrimethylsilylation of Styrenes with Anti-Markovnikov Selectivity Using Hexamethyldisilane". Org. Lett. 2022, 24, 8735
64. Zheng, Y.-Q.; Li, C.-L.; Liu, W.-B.*; Yu, Z.-X.*"DFT Study of Mechanism and Stereochemistry of Nickel-Catalyzed trans-Arylative Desymmetrizing Cyclization of Alkyne-Tethered Malononitriles". J. Org. Chem. 2022, 87, 16079
63. Cai, J.*; Cen, K.; Shen, W.; Bai, L.-G.; Liu, W.-B.*"[2+2+2] Cycloaddition of Nitriles to Enantioenriched and Highly Substituted Pyridines". Chem Catalysis. 2022, 2, 2889
62. Dong, Z.; Zhong, D.*; Li, Z.-M.; Liu, W.-M.; Zhao, J.; Liu, W.-B.*"Palladium-Catalyzed Stereospecific Coupling of BINOL-bistriflates and Zinc Cyanide and Applications in the Synthesis of 1,1'-Binaphthyl-2,2'-bisoxazolines (BOXAX)" . Synlett 2022, 33, 1837
61. Chen, Z.-H.; Sun, R.-Z.; Yao, F.; Hu, X.-D.; Xiang, L.-X.; Cong, H.-J; Liu, W.-B.*"Enantioselective Nickel-Catalyzed Reductive Aryl/Alkenyl–Cyano Cyclization Coupling to All-Carbon Quaternary Stereocenters". J. Am. Chem. Soc. 2022, 144, 4776
60. Zhang, X.-W.; Zhu, M.-H.; Zeng, H.-X.; Li, Q.-Y.; Liu, W.-B.*"Precatalyst-Enabled Selectivity: Enantioselective NiH-catalyzed anti-Hydrometalative Cyclization of Alkynones to Endo- and Hetero-cyclic Allylic A lcohols". Angew. Chem. Int. Ed. 2021, 60, 27225
59. Zhang, H.; Li, W.; Hu, X.-D.; Liu, W.-B.*"Enantioselective Synthesis of Fused Isocoumarins via Palladium Catalyzed Annulation of Alkyne-Tethered Malononitriles". J. Org. Chem. 2021, 86, 10799
58. Zhao, J.; Huang, H.-G.; Li, W.; Liu, W.-B.*"FeCl2‑Mediated Regioselective Aminochlorination and 2 Aminoazidation of Styrenes with Trifluoromethanesulfonyl Azide". Org. Lett. 2021, 23, 5102
57. Zheng, Y.-Q.; Liu, W.-B.*"Rhodium-Catalyzed Regio- and Enantio-selective Allylic Amination of Racemic 1,2-Disubstituted Allylic Phosphates". Chinese Journal of Organic Chemistry., 2021, Invited highlight.
56. Zhu, M.-H.; Zhang, X.-W.; Usman, M.; Cong, H.-J.; Liu, W.-B.*"Palladium-Catalyzed (4+4) Annulation of Silacyclobutanes and 2-Iodobiarenes to Eight-Membered Silacycles via C–H and C–Si Bonds Activation". ACS Catal. 2021, 11, 5703
55. Wu, L.-Y.; Zhong, D.; Liu, W.-B.*"Ligand-Free Iron-Catalyzed Intramolecular Amination of C(sp3 )—H Bond for the Synthesis of Imidazolinones". Chinese Journal of Organic Chemistry., 2021, Invited highlight.
54. Hu, X.-D.; Chen, Z.-H.;Zhao, J.; Sun, R.-Z.; Zhang, H.; Qi, X.-T.; Liu, W.-B.*"Enantioselective Synthesis of a-All-Carbon Quaternary Center-Containing Carbazolones via Amino-Palladation/Desymmetrizing Nitrile Addition Cascade". J. Am. Chem. Soc. 2021, 143, 3734.
53. Zhang, H.; Liu, W.-B.* "Highly Enantioselective Iridium-Catalyzed Coupling Reaction of Vinyl Azides and Racemic Allylic Carbonates". Chinese Journal of Organic Chemistry., 2020, 40, 4382. Invited highlight.
52.Cai, J. (co-first author); Bai, L.-G. (co-first author); Zhang, Y.-L.; Wang, Z.-K.; Yao, F.; Peng, J.-H.; Yan, W.; Wang,Y.; Zheng, C.; Liu, W.-B.* "Ni-Catalyzed Enantioselective [2+2+2] Cycloaddition of Malononitriles with Alkynes". Chem., 2021, 7, 799.
51. Zhong, D. (co-first author); Wu, L.-Y. (co-first author); Wang, X.-Z.; Liu, W.-B.* "Iron-Catalyzed Intramolecular C—H Amidation of N-Benzoyloxyureas". Chin. J. Chem., 2021, 39, 855.
50. Huang, H.-G.; Li, W.; Zhong, D.; Wang, H.-C.; Zhao, J.; Liu, W.-B.* "Trifluoromethanesulfonyl azide as a bifunctional reagent for metal-free azidotrifluoromethylation of unactivated alkenes". Chem. Sci., 2021, 12, 3210.
49. Zhang, X.-W.; Zhang, H.; Wang, H.-C.; Zhu, M.-H.; Cong, H.-J.; Liu, W.-B.* "Pd-Cat alyzed Arylation/Aza-Michael Addition Cascade to C2- Spiroindolines and Azabicyclo[3.2.2]nonanones". Chem. Commun., 2020, 56, 12013.
48. Zhang, Y.; Zhong, D.; Usman, M.; Xue P.; Liu, W.-B.* "Iron-Catalyzed Primary C–H Amination of Sulfamate Esters and Its Application in the Synthesis of Azetidines". Chin. J. Chem. 2020, 38, 1651.
47. Lu, Z.-W (co-first author); Hu, X.-D. (co-first author); Zhang, H.; Zhang, X.-W.; Cai, J.; Usman, M.; Cong, H.; Liu, W.-B.* "Enantioselective Assembly of Cycloenones with a Nitrile-Containing All-Carbon Quaternary Center from Malononitriles Enabled by Ni Catalysis". J. Am. Chem. Soc. 2020, 142, 7328.
46. Usman, M. (co-first author); Hu, X.-D. (co-first author); Liu, W.-B.* "Recent Advances and Perspectives in the Synthesis and Applications of Tetrahydrocarbazol-4-ones" Chin. J. Chem. 2020, 38, 737. Dedicated to the 30th Anniversary of State Key Laboratory of Organometallic Chemistry (Invited contribution).
45. Cai, J.; Wang, Z.-K.; Zhang, Y.-H.; Yao, F.; Hu, X.-D.; Liu, W.-B.* "Synthesis of Polysubstituted 2‐Naphthols by Palladium‐Catalyzed Intramolecular Arylation/Aromatization Cascade". Adv. Synth. Catal. 2020, 362, 1303.
44. Wu, L.-Y.; Usman, M.; Liu, W.-B.* "Enantioselective Iron/Bisquinolyldiamine Ligand-Catalyzed Oxidative Coupling Reaction of 2-Naphthols". Molecules 2020, 25, 852. Invited contribution to the Special Issue Recent Advances in Iron Catalysis.
43. Wei Q.(co-first author); Cai, J.(co-first author); Hu, X.-D.; Zhao J.; Cong, H.-J.; Zheng C.; Liu, W.-B.*."Enantioselective Access to All Carbon Quaternary Center-Containing Cyclohexanones by Palladium-Catalyzed Desymmetrization". ACS Catal. 2020, 10, 216.
42. Li, W.; Usman, M.; Wu, L.-Y.; Liu, W.-B.*."Synthesis of 2,3-Ring Fused Pyrroles via Cu-Catalyzed 5-exo-dig Annulation of Alkyne-tethered Enaminones". J. Org. Chem. 2019, 84, 15754.
41. Cai, J.; Wang, Z.-K.; Usman, M.; Lu, Z.-W.; Hu, X.-D.; Liu, W.-B.*. "Enantioselective Synthesis of β-Quaternary Carbon-Containing Chromanes and 3,4-Dihydropyrans via Cu-Catalyzed Intramolecular C–O Bond Formation". Org. Lett. 2019, 21, 8852.
40. Zhu, M.-H.(co-first author); Yu, C.-L.(co-first author); Feng, Y.-L.; Usman, M.; Zhong, D.-Y; Wang X.; Nesnas N.; Liu, W.-B.*."Detosylative (Deutero)alkylation of Indoles and Phenols with (Deutero)alkoxides". Org. Lett. 2019, 21, 7073.
39. Zhong, D.; Wu D.; Zhang Y.; Lu Z.-W.; Usman, M.; Liu W.; Lu, X.-Q.; Liu, W.-B.*. "Synthesis of Sultams and Cyclic N-Sulfonyl Ketimines via Iron-Catalyzed Intramolecular Aliphatic C-H Amidation". Org. Lett. 2019, 21, 5808.
38. Li, W.; Dong, Z.; Zhang Y.; Zeng Z.; Usman, M.; Liu, W.-B.*. "Cu-Catalyzed Arylation/Acyl Migration Cascade Reaction of Enaminones: Access to N‑Fused Polycyclic and 2,3-DisubstitutedIndoles". J. Org. Chem. 2019, 84, 7995.
37. Liu, W. (co-first author); Zhong, D.-Y (co-first author); Yu, C.-L.; Zhang Y.; Wu, D.; Feng, Y.-L.; Cong, H.-J.; Lu, X.-Q.; Liu, W.-B.*. "Iron-Catalyzed Intramolecular Amination of Aliphatic C-H Bonds of Sulfamate Esters with High Reactivity and Chemoselectivity". Org. Lett. 2019, 21, 2673.
36. Usman, M.; Zhang, X.-W.; Wu, D.; Guan, Z.-H.; Liu, W.-B.*. "Application of Dialkyl Azodicarboxylates Frameworks Featuring Multi-Functional Properties". Org.Chem. Front.(Review) 2019, 6, 1905.
34. Usman, M.; Zhang, X.-W.; Liu, W.-B.*. "Silicon-Tethered Frameworks as Directing Groups for Carbon–Carbon and Carbon–Heteroatom Bond Formation". Synthesis (Invited review), 2019, 51, 1529.
33. Dong, Z. (co-first author); Zhang, X.-W. (co-first author); Li, W.; Li, Z.-M.; Wang, W.-Y.; Zhang, Y.; Liu, W.; Liu W.-B.*. "Synthesis of N-Fused Polycyclic Indoles via Ligand-Free Palladium-Catalyzed Annulation/Acyl Migration Reaction". Org. Lett. 2019, 21, 1082. (Highlighted by Synfact)
32. Wang X.; Zhu, M.-H.; Schuman D. P.; Zhong, D.-Y.; Wang, W.-Y.; Wu, L.-Y.; Liu W.; Stoltz B. M.; Liu, W.-B.*. "General and Practical KOMe/Disilane-Mediated Dehalogenative Deuteration of (Hetero)Arylhalides". J. Am. Chem. Soc. 2018, 140, 10970.
31.Cai, J.-H.; Wei Q.; Hu, X.-D.; Zhang Y.; Li, W.-S.; Cong, H.-J.; Liu W.; Liu, W.-B.*. "Enantioselective Construction of Bridgehead Quaternary Carbon Containing Bicyclo[3.3.1]nonanes by Palladium-Catalyzed-Desymmetric Arylation". Synthesis 2018, 50, 1661.
30. Liu, W.-B.(co-first author); Schuman, D. P.(co-first author); Yang, Y.-F.(co-first author); Toutov, A. A.; Liang, Y.; Klare, H. F. T.; Nesnas, N.; Oestreich, M.; Blackmond, D. G.; Virgil, S. C.; Banerjee, S.; Zare, R. N.; Grubbs, R. H.; Houk, K. N.; Stoltz, B. M. "Potassium tert-Butoxide-Catalyzed Dehydrogenative C−H Silylation of Heteroaromatics: A Combined Experimental and Computational Mechanistic Study". J. Am. Chem. Soc. 2017, 139, 6867.
29. Banerjee, S.(co-first author); Yang, Y.-F.(co-first author); Jenkins, I. D.(co-first author); Liang, Y.; Toutov, A. A.; Liu, W.-B.; Schuman, D. P.; Grubbs, R. H.; Stoltz, B. M.; Krenske, E. H.; Houk, K. N.; Zare, R. N. "Ionic and Neutral Mechanisms for C−H Bond Silylation of Aromatic Heterocycles Catalyzed by Potassium tert-Butoxide". J. Am. Chem. Soc. 2017, 139, 6880.
28. Toutov, A. A.; Betz, K. N.; Schuman, D. P.; Liu, W.-B.; Fedorov, A.; Stoltz, B. M.; Grubbs, R. H. "Alkali Metal-Hydroxide-Catalyzed C(sp)-H Bond silylation". J. Am. Chem. Soc. 2017, 139, 1668.
27. Liu, W.-B. (co-first author); Okamoto, N. (co-first author); Alexy, E. J.; Hong, A. Y.; Tran, K.; Stoltz, B. M. "Enantioselective gamma-Alkylation of alpha, beta-Unsaturated Malonates and Ketoesters by a Sequential Ir-Catalyzed Asymmetric Allylic Alkylation/Cope Rearrangement". J. Am. Chem. Soc. 2016, 138, 5234.
26. Toutov, A. A. (co-first author); Liu, W.-B. (co-first author); Stoltz, B. M; Grubbs, R. H. "Potassium tert-Butoxide-Catalyzed Dehydrogenative Cross-Coupling of Heteroarenes with Hydrosilanes". Org. Synth. 2016, 93, 263.
25. Zhang, X.; Liu, W.-B.; Cheng, Q.; You, S.-L. "Iridium-Catalyzed Asymmetric Allylic Amination Reactions with N-Aryl Phosphoramidite Ligands". Organomet. 2016, 35, 2467.
24. Zhang, X.; Liu, W.-B.; Tu, H.-F.; You, S.-L. "Ligand-Enabled Ir-Catalyzed Intermolecular Diastereoselective and Enantioselective Allylic Alkylation of 3-Substituted Indoles". Chem. Sci. 2015, 6, 4525.
23. Toutov, A. A.(co-first author); Liu, W.-B.(co-first author); Betz, K. N.; Fedorov, A.; Stoltz, B. M.; Grubbs, R. H. "Silylation of C-H Bonds in Aromatic Heterocycles by an Earth-Abundant Metal Catalyst". Nature, 2015, 518, 80.
22. Liu, Y.-Y.; Han, S. J., Liu, W.-B.; Stoltz, B. M. "Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules". Acc. Chem. Res. 2015, 48, 740.
21. Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L. "Enantioselective Synthesis of Pyrrole-Based Spiro- and Polycyclic Derivatives by Iridium-Catalyzed Asymmetric Allylic Dearomatization and Controllable Migration Reactions". Angew. Chem. Int. Ed. 2015, 54, 8475.
20. Toutov, A. A.(co-first author); Liu, W.-B.(co-first author); Betz, K. N.; Stoltz, B. M.; Grubbs, R. H. "Catalytic C-H Bond Silylation of Aromatic Heterocycles". Nature Protocols. 2015, 10, 1897.
19. Liu, W.-B.; Reeves, C. M.; and Stoltz, B. M. "Enantio-, Diastereo- and Regioselective Iridium-Catalyzed Asymmetric Allylic Alkylation of Acyclic β-Ketoesters". J. Am. Chem. Soc. 2013, 135, 17298.
18. Liu, W.-B.; Reeves, C. M.; Virgil, S. C.; and Stoltz, B. M. "Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters via Ir-Catalyzed Regio‑, Diastereo‑, and Enantioselective Allylic Alkylation and Applications in Sequential Pd Catalysis". J. Am. Chem. Soc. 2013, 135, 10626.
17. Bennett, N. B.; Duquette, D. C.; Kim, J. M.; Liu, W.-B.; Marziale, A. N.; Behenna, D. C.; Virgil, S. C.; and Stoltz, B. M. "Expanding Insight into Asymmetric Palladium‐Catalyzed Allylic Alkylation of N‐Heterocyclic Molecules and Cyclic Ketones". Chem. Eur. J. 2013, 19, 4414.
16. Zhang, X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L. "Ruthenium-Catalyzed Intramolecular Allylic Dearomatization Reaction of Indole Derivatives". Org. Lett. 2013, 15, 3746.
15. Liu, W.-B.; Zhang, X.; Dai, L.-X.; You, S.-L. "Asymmetric N-Allylation of Indoles Through the Iridium-Catalyzed Allylic Alkylation/Oxidation of Indolines". Angew. Chem. Int. Ed. 2012, 51, 5183.
14. Liu, W.-B.; Zheng, C.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L. "Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies". J. Am. Chem. Soc. 2012, 134, 4812.
13. Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L. "Asymmetric Dearomatization of Pyrroles via Ir-catalyzed Allylic Substitution Reaction: Enantioselective Synthesis of Spiro-2H-Pyrroles". Chem. Sci. 2012, 3, 205.
12. Su, H.; Xie, Y.; Liu, W.-B.; You, S.-L. "Methyl-Monofluorination of Ibuprofen Selectively Increases Its Inhibitory Activity Toward Cyclooxygenase-1 Leading to Enhanced Analgesic Activity and Reduced Gastric Damage in Vivo". Bioorg. Med. Chem. Lett. 2011, 21, 3578.
11. Ye, K.-Y.; He, H.; Liu, W.-B.; Dai, L.-X.; Helmchen, G.; You, S.-L. "Iridium-Catalyzed Allylic Vinylation and Asymmetric Allylic Amination Reactions with o-Aminostyrenes". J. Am. Chem. Soc. 2011, 133, 19006.
10. Wu, Q.-F.; Liu, W.-B.; Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.;You, S.-L. "Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization of Phenols". Angew. Chem. Int. Ed. 2011, 50, 4455.
9. Liu, W.-B.; He, H.; Dai, L.-X.; You, S.-L. "A One-Pot Palladium-Catalyzed Allylic Alkylation and Wittig Reaction of Phosphorus Ylides". Chem. – Eur. J. 2010, 16, 7376.
8. Wu, Q.-F.; He, H.; Liu, W.-B.; You, S.-L. "Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation Reactions". J. Am. Chem. Soc. 2010, 132, 11418.
7. Xu, Q.-L.; Liu, W.-B.; Dai, L.-X.; You, S.-L. "Iridium-Catalyzed Enantioselective Allylic Substitution of O-Allyl Carbamothioates". J. Org. Chem. 2010, 75, 4615.
6. Xia, J.-B.; Liu, W.-B.; Wang, T.-M.; You, S.-L. "Enantioselective Synthesis of 3-Azabicyclo[4.1.0]heptenes and 3-Azabicyclo[3.2.0]heptenes by Ir-Catalyzed Asymmetric AllylicAmination of N-TosylPropynylamine and Pt-Catalyzed Cycloisomerization". Chem. – Eur. J. 2010, 16, 6442.
5. He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L. "Enantioselective Synthesis of 2,3-Dihydro-1H-benzo[b]azepines via Ir-Catalyzed Tandem AllylicVinylation/Amination Reaction". Angew. Chem. Int. Ed. 2010, 49, 1496.
4. He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L. "Ir-Catalyzed Cross-Coupling of Styrene Derivatives with Allylic Carbonates: Free Amine Assisted Vinyl C-H Bond Activation". J. Am. Chem. Soc. 2009, 131, 8346.
3. Liu, W.-B.; He, H.; Dai, L.-X.; You, S.-L. "Synthesis of 2-Methylindoline- and 2-Methyl-1,2,3,4-tetrahydroquinoline-Derived Phosphoramidites and Their Applications in Iridium-Catalyzed Allylic Alkylation of Indoles". Synthesis 2009, 2076.
2. Liu, W.-B.; Zheng, S.-C.; He, H.; Zhao, X.-M.; Dai, L.-X.; You, S.-L. "Iridium-catalyzed Regio- and EnantioselectiveAllylic Alkylation of Fluorobis(phenylsulfonyl)methane". Chem. Commun. 2009, 6604.
1. Liu, W.-B.; He, H.; Dai, L.-X.; You, S.-L. "Ir-Catalyzed Regio- and Enantio-selective Friedel–Crafts-Type Allylic Alkylation of Indoles". Org. Lett. 2008, 10, 1815.
Book Chapters:
1. Liu, W.-B.; Xia, J.-B.; You, S.-L. "Iridium-Catalyzed Asymmetric Allylic Substitutions".Topics in Organometallic Chemistry, U. Kazmaier (Ed), 2012, 38, 155.
Patents:
1. You, S.-L.; Liu, W.-B. "Phosphor-nitrogen ligand derived from tetrahydroquinoline and indoline, preparation method and use thereof". CN101508702 A.
2. You, S.-L.; Zhuo, C.-X.; Liu, W.-B. "Chirality phosphine nitrogen compound containing N-aryl as well as synthetic method and application thereof".CN103087106 B.
3. Su, H.;Xie, Y.-L.;You, S.-L.; Liu, W.-B. "Medical use of (S)-3-fluoro-2-(4-isobutyl phenyl) propionic acid". CN102068422 B.
4. You, S.-L.; Liu, W.-B. "3-(substituted bisulfonyl fluromethane)-1-propylene compound, synthetic method and applications thereof". CN101565393 B.
5. You, S.-L.; Liu, W.-B. "Process for synthesizing 3-indole-1-propylene compounds and uses thereof". CN101245046 B.
6. Silylation of aromatic heterocycles by disilanes using potassium alkoxide catalysts. US 9556080
7. Silylation of aromatic heterocycles by disilanes using potassium alkoxide catalysts. WO2016/100606
8. Base-catalyzed silylation of terminal olefinic C–H bonds. US 9556206
9. Silylation of aromatic heterocycles by earth abundant transition-metal-free catalysts. US 9809607
10. Base-catalyzed silylation of terminal olefinic C–H bonds. US 10059726
11. Base-catalyzed silylation of terminal alkyne C–H bonds US 10072030
12. Preparation Of Silylamines By The Dehydrogeative Coupling Of N–H And Si–H Bonds. US 10125153